Immunicum AB
Immunicum reports continued promising survival data for INTUVAX-treated renal cancer patients
Immunicum AB 03.12.2014 08:30 Dissemination of a Adhoc News, transmitted by DGAP - a service of EQS Group AG. The issuer is solely responsible for the content of this announcement. --------------------------------------------------------------------------- Gothenburg, Sweden, 2014-12-03 08:30 CET (GLOBE NEWSWIRE) -- Immunicum AB (publ) today announced continued promising data from a phase I/II trial in patients with metastatic renal cell carcinoma. The median survival in the subgroup of five individuals who were initially classified as high-risk patients now stands at 19.8 months, compared with an expected median survival of nine months following current standard therapy. Seven of the eleven evaluable patients in the study, of which two belong to the original group of five high-risk patients, are still alive. In total, six of eleven patients have now received add-on therapy with tyrosine kinase inhibitors (TKI) due to tumor growth. Three of these patients (all with massive infiltration of CD8+ T cells in the removed kidney tumor) have noted a pronounced and prolonged regression of metastases. Continued monitoring is necessary to clarify the effect on survival in patients with a slightly less aggressive disease (intermediate mRCC). Five of the six patients in this subgroup are still alive, three of which have achieved a survival time of more than two years. - It is gratifying that the median survival in the INTUVAX-treated renal cancer patients continues to increase. We are now preparing a comprehensive phase II study in the same indication and expect this to be able to start in early 2015, says Immunicum's CEO, Jamal El-Mosleh. The purpose of the phase I/II study was to document the adverse event profile and immunological effects, and to follow the survival of patients with metastatic renal cell carcinoma after treatment with two INTUVAX injections. For further information, please contact: Jamal El-Mosleh, CEO, Immunicum Phone: +46 (0) 31 41 50 52 jamal.el-mosleh@immunicum.com Alex Karlsson-Parra, CSO, Immunicum Phone: +46 (0) 705 16 75 79 alex.karlsson-parra@immunicum.com The company's Certified Adviser is Redeye AB Phone: +46 (0) 8 545 013 31. www.redeye.se About Immunicum AB (publ) Immunicum AB (publ) develops vaccines for the treatment of tumor diseases. A phase II study of the company's most advanced project - INTUVAX(R) against renal cancer - is expected to start in early 2015. The project portfolio contains three further projects against various tumor diseases, including liver cancer. www.immunicum.com News Source: NASDAQ OMX 03.12.2014 The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases. Media archive at www.dgap-medientreff.de and www.dgap.de --------------------------------------------------------------------------- Language: English Company: Immunicum AB Sweden Phone: Fax: E-mail: Internet: ISIN: SE0005003654 WKN: End of Announcement DGAP News-Service ---------------------------------------------------------------------------
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